The two-day Basic Science Seminar at ILC 2022 focused on the central role of the liver as a site of increasingly common metabolic disorders related to the accumulation of hepatic fat. From a macroscopic to a microscopic point of view, the seminar explored organ crosstalk and multicellular communication that drives metabolic diseases. The various kinds of expertise of speakers will not only highlighted the pathways impaired in fatty liver disease, but also provided novel potential therapeutic strategies to tackle this disease.

The seminar aimed to foster interaction between leaders-in-the-field and the audience. It contained multiple short duo-lectures, with first a more general ten-minute overview of the topic, followed by a more in-depth ten-minute presentation by a talented fellow, and finally an extensive Q&A of 10 minutes. In total 5 such sessions will extensively covered the field of fatty liver disease and associated complications, such as fibrosis and cancer.