This page is designed to provide you with an array of useful resources including articles, accounts from healthcare professionals, calls for abstracts and statements related to COVID-19 and the liver.
You are welcome to send us relevant articles, links and testimonies from healthcare workers for us to share once we’ve curated them.
Please send your materials to firstname.lastname@example.org
Care of patients with liver disease during the COVID-19 pandemic: EASL-ESCMID Position Paper
In response to the COVID pandemic, EASL and the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) – have issued a Position Paper providing recommendations for clinicians on caring for patients with liver diseases and for liver transplant recipients.
In addition to recommendations, this Position Paper provides a flowchart and an overview of current treatment options, to help clinicians with their decision-making during this resource-strapped time of COVID-19.
EASL webinars & webcasts
EASL has launched a series of webinars and webcasts relating to COVID-19. The participants are world-renowned scientists and clinicians that discuss and share their knowledge about the latest developments of the virus.
Webinar 1: EASL – WHO on COVID-19 and the Liver
Testimonials on dealing with the public health crisis
Prof. Jessica Zucman-Rossi
Liver Nurse Educator, Leeds Liver Unit
Lecturer in Adult Nursing, University of Leeds
Chair, EASL Nurses and Allied Health Professionals Task Force
Hepatology nurse Pamela Ballotta
Multivisceral Transplant Unit and Unit of Gastroenterology
Azienda Ospedaliera di Padova
Prof. Luca Valenti
EASL Scientific Committee member
Associate Professor of Internal Medicine, University of Milan
COVID-19 related papers from the Journal of Hepatology and JHEP Reports
The “EASL COVID-19 article collection” contains articles dealing with COVID-19 and the liver published in the two EASL journals, Journal of Hepatology and JHEP Reports. This initiative aims at facilitating access to research that can be critically relevant for the treatment of liver patients during the pandemic.
The articles will appear in the collection shortly after their publication in their respective journals.
News from the EASL supported COVID-Hep registry
Press release, 21/05/2020
A new international study has found increased mortality rates from COVID-19 among people with chronic liver disease and cirrhosis and has called for patients with worsening liver function to be tested for coronavirus.
The researchers, led by teams at Oxford University Hospitals NHS Foundation Trust and the University of North Carolina, set up an international registry (the EASL supported COVID-hep registry) to collect clinical details of patients with chronic liver disease and cirrhosis who develop COVID-19. Between 25 March 2020 and 20 April 2020, 152 cases were submitted to the registry, over 95% of which were hospitalised. Patients with cirrhosis had poor outcomes with an overall death rate of 40 percent. Those with advanced disease called decompensated cirrhosis had the highest rate of death (between 43 and 63 percent), compared with 12 percent for patients with liver disease but without cirrhosis.
The EASL supported COVID-Hep registry was launched on 23 March 2020. EASL is actively supporting this initiative: http://covid-hep.net
Accordingly, EASL encourages healthcare professionals to share the EASL supported COVID-Hep registry among its networks. The new registry was launched at the University of Oxford, UK to collect data on patients, with liver disease at any stage or liver transplants, that have developed laboratory-confirmed COVID-19.
The registry is sending weekly updates on submissions received. Busy healthcare workers are submitting data for patients, with liver disease at any stage or liver transplants, that have developed laboratory-confirmed COVID-19.
As of 26 May, week 9, data collected (combined with data from SECURE-cirrhosis, who are covering the Americas, China, Japan, and Korea) has grown to 649 cases reported from 30 countries.
Webinars on COVID-19 and the liver
The APASL Steering Committee is pleased to launch APASL COVID-19 Webinars, a series of seven webinars drawing on the experience of doctors from the Asian Pacific, who faced COVID-19 in this region before it reached other parts of the world. The webinars are intended for these doctors to share their experience with their international peers, to help combat the disease.
Find out on this link all the information about APASL webinars. The webinars are set to run until July 2020.
Journal of Hepatology call for papers on COVID-19
The outbreak of COVID-19 (coronavirus) is of great concern and a considerable challenge for practitioners and public health authorities. Following the initiative of other leading scientific journals, we believe that it is timely, important, and appropriate to share with our Journal of Hepatology readers, as soon as possible, all information available on the possible impact of the infection on the liver and on patients with liver diseases.
We therefore invite authors to send their original data on these topics. We will provide authors with a rapid evaluation and, if their articles are accepted, free access to their content. Of course, as an obligation to our community, we will ensure the same high standards of scientific review for these articles.
External resources on COVID-19
Public health resources
European Centre for Disease Prevention and Control: COVID-19
European Centre for Disease Prevention and Control: today’s data on geographic distribution of COVID-19 cases worldwide
European Commission: Coronavirus response
European Commission: Public health
European Medicines Agency: Coronavirus disease (COVID-19)
World Health Organization: Coronavirus disease (COVID-19) outbreak
World Health Organization: Coronavirus disease (COVID-19) Pandemic
World Health Organization: Q&A on coronaviruses (COVID-19)
British Medical Journal: Coronavirus (covid-19): Latest news and resources
Cell Press: COVID-19 Resource Hub
The Lancet: COVID-19 Resource Centre
New England Journal of Medicine: Coronavirus (Covid-19)
Science: Coronavirus: Research, Commentary, and News
COVID-19 and the liver
The Lancet: COVID-19 and the liver: little cause for concern
The Lancet: Liver injury in COVID-19: management and challenges
Wiley Online, Liver International: Liver injury during highly pathogenic human coronavirus infections
Open access scientific articles
Cell.com: Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
Journal of Clinical Microbiology: The emergence of a novel coronavirus (SARS-CoV-2), their biology and therapeutic options
Nature: Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus
Nature: Epidemiological data from the COVID-19 outbreak, real-time case information
Nature: Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2
BioMed Alliance submits Joint Statement to EU leaders, as COVID-19 threatens medical associations
Subsequent to the disruption caused by the COVID-19 pandemic, EASL and 32 other leading European medical associations – together forming the Biomedical Alliance in Europe (BioMed Alliance) – have submitted a joint statement to EU leaders.