Fibrosis is a global health problem characterized by an excessive growth of fibrous tissue due to chronic inflammation and altered tissue remodelling and repair processes. It occurs in various organs, including the lung, kidney, liver and intestine, and is a key component of important pathologies, including cystic fibrosis, Crohn’s Disease and Non-Alcoholic Fatty Liver Disease. Despite the huge advances made by research in recent years, the molecular mechanisms involved in the development of fibrosis are still unclear; indeed, it would seem that different mechanisms are involved in each of the affected organs.
Importantly, few effective therapeutic options are available, and only for some organs, such as the lung and kidney, with no anti-fibrotic pharmacological treatments available for the intestine or liver. The International Workshop on Liver and Gut Fibrosis – the first to take place, and endorsed by EASL – has been organised to bring together basic scientists and clinical experts working in the field with the purpose of focusing on the molecular mechanisms involved in the different types of fibrosis and determining those that are common to different organs, particularly the gut and liver. In this way, the workshop has been designed to explore options that might improve current therapeutic approaches and to identify new pharmacological targets that will relieve the burden of fibrosis for millions of patients.
We invite those of you who are interested in this topic to join us and some of the most relevant European researchers in the field here in the beautiful Mediterranean city of Valencia, at the beginning of summer, probably one of the best times of the year to visit. We look forward to seeing you.
- Salvador Benlloch, Hospital La Fe, Valencia, Spain
- Marina Berenguer, University of Valencia, Spain
- Ana Blas-García, CIBERehd, Valencia, Spain
- Sara Calatayud, University of Valencia, Spain
- Jesús Cosin-Roger, FISABIO, Spain
- Javier Cubero, Universidad Complutense, Madrid, Spain
- Eugeni Domenech, Hospital Universitari Germans Trias i Pujol, Badalona, Spain
- Juan Manuel Falcón, CICbioGUNE, Derio, Spain
- Rubén Francés, FISABIO-Hospital de Alicante, Alicante, Spain
- Juan Carlos García-Pagán, Hospital Clínic, Barcelona, Spain
- Jordi Gracia-Sancho, IDIBAPS, Barcelona, Spain
- Ángela Nieto, Instituto de Neurociencias de Alicante, Spain
- Gerard Rogler, University Hospital Zurich, Switzerland
- Krista Rombouts, University College, London, UK
- Azucena Salas, Hospital Clínic Barcelona, Spain
- Frank Tacke, Charité-Universitätsmedizin, Berlin, Germany
- Manon Wildenberg, University of Amsterdam, Netherlands