Primary biliary cholangitis (PBC) is a chronic inflammatory
autoimmune cholestatic liver disease, which when untreated will
culminate in end-stage biliary cirrhosis. Diagnosis is usually
based on the presence of serum liver tests indicative of a cholestatic
hepatitis in association with circulating antimitochondrial
antibodies. Patient presentation and course can be diverse and
risk stratification is important to ensure all patients receive a personalised
approach to their care.